Chlorella is a sort of single-celled aquatic organisms which have comparatively just lately gained the standing of “superfoods”, partly because of the complete amino acid profile and excessive content material of omega-Three fatty acids DHA and EPA. It has additionally been reported that it lowers blood strain in people, lowers serum ldl cholesterol, will increase immunity, and even fights most cancers.
In keeping with presently prevailing developments, we must always add chlorella in every single place – to the morning shake, afternoon salad and night snack. It goals to supply well being, youth, excellent sports activities outcomes and a mess of different advantages. However is it actually so?
Plainly chlorella absolutely deserves its good status and superfood standing. Nonetheless, it must be remembered that though chlorella as an organism has existed for billions of years, it couldn’t represent a big a part of the human eating regimen for apparent causes. Subsequently, it must be thought-about as meals from the economic (or trendy) period and because of this must be handled with some precaution. We now have solely just lately understood the chemistry of chlorella within the human physique. In an article from 2002, Armstrong et al.  found lipopolysaccharide (LPS) within the chlorella cell wall. LPS is an endotoxin discovered on the floor of all Gram-negative micro organism corresponding to E. coli or Salmonella and is a powerful activator of the immune system. When LPS binds to receptors on the floor of macrophages (phagocytic cells of the innate immune system), it prompts and induces them to launch proinflammatory cytokines IL-1β, tumor necrosis issue TNFa and nuclear factor-kappa B (NF-κB) . Chlorella, in impact, stimulates our innate immunity by way of LPS, an endotoxin that happens in some lethal micro organism. An excessive amount of LPS results in sepsis, which, for apparent causes, we must always keep away from, however even low doses of chlorella could give undesirable signs. Though a stimulated, lively immune system could also be useful in conditions corresponding to an epidemic of an infectious illness, it’s best to ask what occurs to us when chlorella is an everyday a part of the eating regimen. Persistent publicity to LPS results in continual systemic irritation, which is certainly not wholesome for our physique. Specifically, macrophages activated by LPS within the brain are concerned within the progressive degeneration of dopaminergic neurons and are chargeable for Parkinson’s illness .
However wait, it’s not all!
Is chlorella not by chance on the backside of the water chain? Some unlucky organisms should eat it, so why cannot we? It seems that animals that eat algae, corresponding to crab or shrimp, have developed a mechanism, a novel protein that binds and neutralizes LPS. We people didn’t develop such protection mechanisms. Within the case of chlorella, we see one other manifestation of a widely known evolutionary historical past. Birds eat grain and other people eat birds. Individuals, in contrast to birds, don’t do effectively after they eat uncooked grains. It’s the identical with chlorella. For shrimps it may be a wonderful supply of meals, however for folks (who eat shrimps) not essentially.
If this was not sufficient to dissuade you from utilizing chlorella as an ingredient in each meal, there may be additionally the chance of getting contaminated with viruses. And it is a enormous danger . Sometimes, the virus accommodates genetic details about a handful of viral proteins. Chlorella viruses have greater than 300 genes, most of which code for proteins of unknown perform. The potential of dangerous interactions of those proteins with the conventional functioning of human cells is actual. If the story of one other fallen superfood, aka Klamath Lake cyanobacteria, is any warning, then sooner or later we anticipate a repeat of the Chlorella virus leisure. As the usage of chlorella in meals will increase underneath strain from industrial producers and distributors, the chance of being contaminated by the virus additionally will increase. It might be good if we persist with the examined tremendous merchandise with a full amino acid profile and excessive content material of DHA and EPA – fish and oil obtained from them.
Individuals who for no matter motive refuse to take DHA and EPA from animal sources will do the correct factor in the event that they complement their eating regimen with the omega-3 fatty acids from chlorella as a substitute of consuming all of the chlorella. It’s assumed that extracts from chlorella are freed from LPS and different poisonous substances.
 Armstrong PB, Armstrong MT, Pardy RL, Little one A, Wainwright N., Immunohistochemical demonstration of a lipopolysaccharide within the cell wall of a eukaryote, the inexperienced alga, Chlorella, Biol Bull. 2002 Oct;203(2):203-Four.
 Hsu HY, Jeyashoke N, Yeh CH, Tune YJ, Hua KF, Chao LK, Immunostimulatory bioactivity of algal polysaccharides from Chlorella pyrenoidosa prompts macrophages through Toll-like receptor Four, J Agric Meals Chem. 2010 Jan 27;58(2):927-36.
 Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT, Systemic LPS causes continual neuroinflammation and progressive neurodegeneration, Glia. 2007 Apr 1;55(5):453-62.
 Van Etten JL, Uncommon life fashion of big chlorella viruses, Annu Rev Genet. 2003;37:153-95.