Fluoride supplements for expectant ladies to avoid decays in their youngsters


Pregnancy is a major life changing event for all women, but this study shows that women who are depressed during pregnancy are also at risk of reduced breastfeeding initiation and premature delivery

A variety of evaluations have actually shown the advantages of topical fluoride in decays avoidance. Placenta transfer of fluoride is feasible although the device undergoes debate. There is the opportunity that fluoride might be included right into teeth creating in utero, so fluoride supplements taken throughout maternity might protect against decays in their youngsters.

The purpose of this Cochrane testimonial was to review the impacts of ladies taking fluoride supplements (tablet computers, decreases, lozenges or eating periodontal) compared to no fluoride supplements while pregnant to avoid decays in the baby teeth of their youngsters.


Searches were performed in the Cochrane Oral Health’s Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) Medline, Embase, LILACS BIREME Virtual Health Library CINAHL United States National Institutes of Health Ongoing Trials Register (ClinicalTrials.gov) as well as the World Health Organization International Clinical Trials Registry Platform data sources without any constraints on language or day.

Randomised regulated tests (RCTs) of fluoride supplements (tablet computers, decreases, lozenges or eating periodontal) offered to ladies while pregnant with the purpose of protecting against decays in the baby teeth of their youngsters were taken into consideration. 2 customers individually evaluated the research studies, drawn out information as well as analyzed danger of predisposition. Total research top quality was analyzed making use of the GRADE strategy.


  • Only 1 RCT at a high danger of predisposition was consisted of.
  • 1175youngsters were birthed to individuals, at 3 years 938 youngsters were subsequented (464in fluoride team, 484 in sugar pill team). 798 youngsters were subsequented at 5 years (398fluoride, 400 sugar pill).
  • There was no analytical distinction in corroded or loaded baby tooth surface areas( dfs) or % of youngsters with decays at 3 years or 5 years.
  • 3 years, danger proportion (RR) = 1.46, (95% CI; 0.75to 2.85)
  • 5 years, RR = 0.84, (95% CI; 0.53to 1.33)
  • Incidence of fluorosis at 5 years was comparable in between the teams


The writers ended:–

There is no proof that fluoride supplements taken by ladies while pregnant work in protecting against tooth decays in their spawn.


As the writers keep in mind, the academic weak point of systems bordering placental transfer of fluoride as well as worries connected to direct exposure while pregnant taken along with an absence of current research studies as well as boosted understanding concerning topical fluoride raising essential concerns regarding whether study on this subject need to be offered any kind of top priority.


Primary paper

Takahashi R, Ota E, Hoshi K, Naito T, Toyoshima Y, Yuasa H, Mori R, Nango E. Fluoride supplementation (with tablets, drops, lozenges or chewing gum) in pregnant women for preventing dental caries in the primary teeth of their children.
Cochrane Database of Systematic Reviews 2017, Issue10 Art. No.: CD011850 DOI: 10.1002/14651858 CD011850 pub2.

Other referrals

Cochrane Oral Health Group Blog – No evidence that fluoride supplements taken by pregnant women prevent tooth decay in their babies

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